isifinyeto

IKomidi Lephothifoliyo Lezempilo libize ingqungquthela ye-inthanethi ngevidiyo ezokwaziswa nguNgqongqoshe kanye noMnyango Wezempilo mayelana nesu lokukhishwa komgomo we-COVID-19 kanye nezinye izindaba zokunakekelwa kwezempilo ezihlobene nalolu bhubhane.

UNgqongqoshe Wezempilo umemezele ukuthi iNingizimu Afrika izothola imithamo yokugoma eyisigidi esivela eSerum Institute of India ngoJanuwari 1 kanye neminye imithamo eyizi-2021 500 ngoFebhuwari 000.

UNgqongqoshe uthathele iKomidi ekucabangeni mayelana nokukhishwa komgomo. Uhlelo luwukuba abantu abayizigidi ezingama-40 bagonywe ezinyangeni eziyi-12 - abagomi abagcwele abayizi-6 300, bajove abantu abangafika kwabangama-50 ngosuku. UNgqongqoshe uthe okuwukuphela kwendlela yokuzivikela [ku-Covid-19] izovela ohlelweni lokugoma, okungenani u-67% wabantu baseNingizimu Afrika okudingeka bathole umgomo we-Covid-19 ukuze umjikelezo wokudluliselwa yephulwe. Kwagqanyiswa ukuthi uhulumeni nguyena yedwa ozothenga lo mgomo. I-SA kulindeleke ukuthi ithole isabelo sayo semithi yokugoma i-Covax ngo-Ephreli kodwa kuphinde kube nezingxoxo nabakhi bomgomo. Yize uMnyango kaMgcinimafa uzothwala “umthwalo omkhulu” wokuthola umuthi wokugoma, kuzophenywa ezinye izindlela ezimbili zezimali: ukucela izikimu zezokwelapha ezizimele ukuthi zixhase ngemithi yokugoma nokucela abanikeli nebhizinisi ukuthi banikele.

Isethulo siveze izinkinga ezihlobene ne-epidemiology kanye nokugadwa kwemithi yokugoma; izitayela ezimweni ezintsha, ukulaliswa esibhedlela kanye nokufa; uhlaka lokusetshenziswa komgomo; izimiso ezibalulekile zokukhishwa; ukuhlonzwa kanye nokubekwa eqhulwini kwabantu abathile okuhlosiwe; indlela yezigaba yokwethulwa komgomo; izindaba zokulawula; ukusatshalaliswa komgomo kanye nezindaba zokuphepha; izidingo zensiza; ukuphepha, ukusebenza kahle, ukuthatha, kanye nomthamo wesibili; ukuxhumana nomphakathi, ukuqondisa nokuqeqeshwa kwababambe iqhaza; izindima nezibopho zoMnyango Wezempilo Kazwelonke kanye nezifundazwe; futhi ekugcineni isabelomali esiyinkomba sesu lokukhishwa.

Mayelana nokwanda kwesibili kweCovid-19 eNingizimu Afrika, uNgqongqoshe ubike ukuthi kunesidingo esikhulu semibhede yasesibhedlela kanye nomoya-mpilo, okwenza kudingeke “ukuvuselelwa” kwemibhede ebikade ingasasebenzi phambilini.

Ezifundazweni ezifana ne-Eastern Cape kanye ne-Western Cape, izibalo zokutheleleka manje sezingaphezu kwalokho ezazikhona eqophelweni eliphezulu legagasi lokuqala ngo-2020, kanti KwaZulu-Natal cishe isibalo seziguli ezilaliswa esibhedlela sicishe siphindeke kabili njengoba ngo-2020.

Amalungu eKomidi abuze imibuzo ebukhali mayelana, phakathi kokunye, ukushayisana, kanye nokubonakala kungalungile kwezibalo ezisemthethweni, ikakhulukazi phakathi kwezifundazwe.

Amalungu azwakalise ukukhathazeka okukhulu mayelana nokuthi ukwelashwa okudingekayo kuyanikezwa yini kuzo zonke iziguli ukuze kwandiswe izinga lokusinda. Kuphinde kwaba nokukhathazeka ngezinga eliphezulu lokufa kweziguli ezingatheleleki nge-COVID19 - kwathiwa "kunabantu abafayo okungafanele bafe". Amalungu athi "aphazamiseke kakhulu" ngesimo ebesisezingeni elibucayi. Amalungu abuze ngokutholakala kwemibhede nomoya-mpilo. UNgqongqoshe ucelwe ukuthi achaze ukuthi kungani izibhedlela zaseNingizimu Afrika bezingakalungiswa yize bekuwusuku lwama-287 lokuvalwa komsebenzi nokuthi kungani izibhedlela zasenkundleni zayekiswa ukusebenza uma kubhekwe amanye amagagasi. Kuthiwa ngesikhathi uhulumeni waseNingizimu Afrika uchitha isikhathi sakhe ngemithetho engaphansi kweleveli yesihlanu, amanye amazwe alungisa imikhakha yawo yezempilo futhi athola imigomo. Amalungu aphikisana nokuthi uhulumeni agcizelele iqhaza lezakhamizi ezithatha izinyathelo zokuvikela (ukugqoka imaski, ukuhlanza ama-sanitising, nokunye okunjalo) lapho kufanele kugcizelelwe ekutholeni imigomo. Ngakho-ke ngenkathi izakhamizi zibambe isiphetho sazo sezingxoxo, umbuso awukawutholi umgomo futhi noMnyango Wezempilo Kazwelonke “wawuhlehla”.

Amalungu azwakalise ngazwi linye ukukhathazeka kwawo mayelana nolwazi olunganembile kanye nokushoda kolwazi olunikezwa umphakathi. UMnyango unxuswe ukuthi ubhekisise kabusha amasu awo okuxhumana mayelana nokungagcini ngokugoma kuphela kodwa nokuqinisekisa ukuthi abantu bafika ngesikhathi ezibhedlela futhi babe nolwazi lokuthi bazinakekele kanjani uma sebephumile. Kuphinde kwaba nokukhathazeka ngokuthi amanye amaLungu akuthola kunzima ukuthola uNgqongqoshe, iPhini likaNgqongqoshe kanye nezinhlaka eziqavile zoMnyango ezaziphendule eKomidini. Amalungu azwakalise ukukhathazeka ngethuba lenkohlakalo mayelana nokuthengwa nokukhishwa komgomo.

Amalungu anxuse ukuthi kucace ukuthi lesi simo sizosingathwa kanjani, nokuthi kuzohlinzekwa kanjani ukwelashwa okufanele emasontweni ezayo.

Kuphinde kwavezwa ukukhathazeka ngokuthi kubukeka sengathi eminye imithi yokugoma ayinakuthengeka e-SA kodwa uhulumeni ubeke eqhulwini ukutakulwa kwe-SA Airways. Okunye okukhathazayo kwasakazwa ukuthi ingabe ukuthengwa kwemithi yokugoma kuzoholela enqubweni “enokuvilapha” ikakhulukazi uma uhulumeni engenakho lokhu okuhlangenwe nakho futhi ukubamba iqhaza kuvimbele abanye abadlali ukuba babambe iqhaza ekukhishweni. Kwagcizelelwa ukuthi kumele kube nohlelo oludidiyelwe futhi oluphelele lomuthi wokugoma olungenziwa umphakathi.

Amalungu abuze ukuthi kwenzekani emingceleni, ukuthi imithi yokugoma iyimpoqo, ukuthi imithi yokugoma ihambe kanjani ngenxa yohlobo olusha lwaleli gciwane elihlonziwe, indima yezinsiza zokwelapha ezizimele, imininingwane ngesikhathi kwenzeka ubudlelwano phakathi kwamazwe amabili nabakhiqizi bomgomo, ukubekwa. labaqeqeshwayo kanye nodokotela asebethathe umhlalaphansi ukuze basize ngokushoda kwabasebenzi, indima yezifundazwe ekukhishweni komgomo, ukunakekelwa kwezempilo kanye nokusebenzisana namanyuvesi.

Kube nemibuzo mayelana nokusetshenziswa kwe-ivermectin nokusebenza kwayo ekwehliseni isimilo nokuthi ngabe iSA Health Products Regulatory Authority yenze ucwaningo olwenele yini kulokhu.

Amanye amaLungu abize umhlangano noNgqongqoshe Wezezimali ukuze achaze imininingwane ethile yezezimali ehlobene nohlelo lokukhishwa, ngaphandle kombono kabani imininingwane ihlale ingacaci.

IKomidi kanye noNgqongqoshe bavumelene ngesidingo sokulawula imihlangano phakathi kwezinhlangothi ukuze kuqinisekiswe ukuthi Amalungu avuselelwa njalo ukuze kuqinisekiswe ukuthi wonke umuntu usekhasini elilodwa ikakhulukazi njengoba iKomidi belibambisene ohlelweni.

Isifinyezo sinikezwe ngu Iqembu Lokuqapha Amalungu ePhalamende

IKomidi lePhothifoliyo Lezempilo lihlangane endaweni yesehlakalo lapho oNgqongqoshe Bezempilo kanye neziNhloko zeMinyango yezeMpilo e-Eastern Cape naseWestern Cape bexoxa ngenqubekelaphambili izifundazwe ezizenzayo ukubhekana nobhubhane lwe-Covid-19 nasekulungiseleleni. ngokuqaliswa komgomo we-Covid-19.

UMnyango wezeMpilo e-Eastern Cape ubikele iKomidi mayelana namacala e-Covid-19 esifundazweni, ukutholakala kwemibhede, ukulaliswa kweCovid-19, ukutholakala kwe-oxygen, ukuhlolwa kwe-Covid-19, izikole zokusoka, ukuhlolwa kwezidumbu, ukutholakala kwemithi kanye nemishini yokuzivikela. kanye nohlelo lokwethulwa kokugoma eMpumalanga Kapa. Ukuqubuka kabusha kwezifo esifundazweni kunyuke kakhulu maphakathi noZibandlela wezi-2020, kodwa ukwanda kwezifo kwenzeke ezifundeni ezahlukene ngezikhathi ezihlukene ngakho-ke igagasi lesibili lalithatha isikhathi eside kunegagasi lokuqala. Lo bhubhane ube nomthelela omkhulu kubasebenzi bezempilo esifundazweni njengoba abangu-9249 bathola ukuthi banalo kwathi abangu-161 babulawa yileli gciwane. Bangu-3.7 million abantu base-Eastern Cape abebezogonyelwa iCovid-19, kuqalwe ngabasebenzi abangu-200 000 bezempilo nabanye abahlobene nayo.

Amalungu eKomidi abuze ukuthi yini engenziwa ngokombono kazwelonke ukusiza uMnyango nokwenza ngcono izinga lempilo yaseMpumalanga Kapa. Kwakuyini izimbangela zalezi zinselelo futhi yini uhulumeni kazwelonke ayengayenza ukuze asize? Singakanani isibalo esijwayelekile sokufa kwabantu e-Eastern Cape uma kuqhathaniswa nesibalo ngesikhathi sobhubhane? Ilungu libuze ukuthi ngabe selwenziwe yini ucwaningo nge-Ivermectin, okumanje ethathwa njengomuthi wezilwane, onikezwe iziguli zase-Eastern Cape ezine-Covid-19. Omunye ubuze ukuthi ngabe isifundazwe senzeni ukuze baphendule labo abanikeze i-Ivermectin kubantu ngaphandle kwemvume yeSouth African Health Products Regulatory Authority (SAPHRA).

Amalungu abekhathazekile ngesibalo sezikhala zezikhala ezingenabantu e-Eastern Cape, ngisho uMnyango wezeMpilo ube neBamba leNhloko yoMnyango. Njengoba isifundazwe besingakakabi nalo uhlelo lokusatshalaliswa komgomo, iKomidi lingaluthola nini uhlelo oluphelele? Ingabe ukufakwa kwe-oxygen ngobuningi okuhleliwe kuqale ngomhlaka-11 Januwari 2021? Ngabe besinesidingo sezibhedlela ezintsha ezifundeni ezintathu esezifinyelele umthamo omkhulu wemibhede noma amawadi angashintshwa abe amawadi e-Covid-19? Ingabe i-Rapid Antigen Test, etuswe yiNhlangano Yezempilo Yomhlaba ukuze ihlonze amacala ezindaweni ezinezinga eliphezulu lokutheleleka, ingasetshenziselwa izinjongo zokuxilonga futhi zaziyini izinzuzo zalokho?

Amalungu aqaphele ukuthi imiphakathi ibingazi ukuthi yenzeni uma abantu begula nge-Covid. Yiziphi izinhlelo i-Eastern Cape enazo ukubhekana nalokhu? Ngabe abasebenzi bezempilo bomphakathi bazonikezwa nini izinkontileka ezigcwele ukuze basize ekulweni nalolu bhubhane? Kungani isifunda saseJoe Gqabi sibhekene nokwanda kwamacala amasha ekubeni inani eliphakeme selidlulile? Kungani iziguli ze-Covid-19 zazixutshwe neziguli ze-TB esibhedlela sase-Empilweni TB? Abesizwa kanjani amakhaza ase-Eastern Cape ukubhekana nokusilela emuva? Ngabe bekulandelwa izinqubo zomthetho ngaphambi kokumbiwa kwezidumbu ukuze zihlolelwe i-Covid-19?

UNgqongqoshe Wezempilo eWestern Cape umemezele ukuthi iWestern Cape ihamba phambili ekulawuleni ubhubhane. Uhlelo lwezobuchwepheshe lwesifundazwe lwathuthukiswa kahle ukuze lube lula ukuqoqwa kolwazi kanye nokubikwa kwezobunhloli nsuku zonke. Ngisho nabashona ngaphandle kohlelo lwezempilo bangahlolwa ngoba uhlelo lubheka imininingwane yoMnyango Wezasekhaya. Isifundazwe besisebenzisana nabasebenzi abahlelekile ezingeni lokuhlela kanti nezimeya zomasipala kudingeke ukuthi zibike ngemininingwane yeCovid-19 kanye nokungenelela komasipala bazo. Isifundo esimqoka kwaba ukuthi umuntu akakwazi ukuqinisa uhlelo ngaphandle kokubhekana nesidingo sabasebenzi bezempilo futhi sebebekwe eqhulwini esifundazweni. IWestern Cape inxuse uMengameli ukuthi avale utshwala amasonto amabili ngesikhathi samaholidi kaKhisimusi ukuze kwehliswe umoya esibalweni esiphezulu sabantu abahlukumezekile ngenxa yotshwala ngaleso sikhathi.

INhloko yoMnyango ikhulume ngeSu lamaphuzu ayi-5 lokuBuyisela kabusha kwe-COVID eWestern Cape obekuhloswe ngalo ukushintsha ukuziphatha komphakathi, ukubhekwa kanye nezimpendulo, ukukhuphula izinga lezinsizakalo zezempilo, ukugcina izinsiza eziphelele kanye nokuvikela abasebenzi bezempilo. Uthe isifundazwe sizonyusa kanjani inkundla yezempilo, silawule nokufa kwabantu wachaza nesu lokugoma lesifundazwe. Zonke izifunda zaseNtshonalanga Kapa zaziyizindawo ezishisayo ngaleso sikhathi, kodwa iGarden Route yayidlule ngokusobala isiqongo segagasi lesibili futhi yayisendleleni eya phansi. I-West Coast ikhombise ukwanda kwamacala, obekukhombisa ukuthi le ndawo isisesigabeni sangaphambili segagasi lesibili kunezinye izifunda. Isifundazwe besinesibalo esikhulu seziguli ezinesifo sikashukela ebesengcupheni enkulu yokungenwa yilolu bhubhane, kodwa amaqhinga ayesefundwe ngendlela yokuphatha abanesifo sikashukela ngesikhathi segagasi lokuqala. Imithi ibihanjiswa emakhaya ukuze iziguli zingayi ezibhedlela ukuyolanda imithi yazo. Isifundazwe besikhathazeke kakhulu ngokuhlukumezeka kwabasebenzi bezempilo obekuzodinga ukwelapheka isikhathi eside.

Amalungu abuze ukuthi yiziphi izinyathelo ezithathwa yiWestern Cape ukubhekana nezinkinga ezihambisana nesifo sikashukela notshwala; uMnyango Wezempilo ukhulume noMkhandlu Wezikhulu Zezifundazwe mayelana nezinga eliphansi lokulandelwa kwemithetho esifundazweni ekugqokeni izifihla-buso kanye nokuqhelelana emphakathini; futhi uthini umbono wesifundazwe ngezwe selikhokhe u-R283 million wokuthola umgomo iSAHPRA eyayingakawugunyazi. Ilungu liphawule ukuthi abanye abasebenzi babike ukuthi bayaphoqwa ukuthi baye emsebenzini noma ngabe begula inqobo nje uma bengenazo izimpawu. Kwakuyiqiniso kangakanani lokho? Obani abebevala izikhala ezingu-1029 zabasebenzi bezempilo abebegula? Ngabe isifundazwe besihlose ukuvala kanjani igebe esilinganisweni se-oxygen esetshenziswa emphakathini uma kuqhathaniswa nezinkampani ezizimele? Ingabe iziguli ebezincishwe amathuba ngenxa yobumpofu ebezithembele ekunakekelweni kwezempilo yomphakathi zibe namathuba aphansi okuthola umoya-mpilo? Ingabe i-Afrox ibiwukuphela komnikezeli womoya-mpilo emazingeni adingekayo? Bekungenzekani uma i-Afrox ingakwazi ukuhlinzeka nge-oxygen eyanele njengoba umoya-mpilo ubuwukungenelela okubalulekile?

Amalungu abuze ukuthi ngabe iWestern Cape iyazi yini ukuthi kungani izifunda ezakhahlanyezwa kabi ngegagasi lokuqala zingahlukumezeki kakhulu egagasini lesibili. Ngabe bekunezinhlelo zokwabiwa, ukuthuthwa kanye nokugcinwa komgomo, hhayi nje kumetro, kodwa nasezifundeni? Belunjani uhlelo lokubhekana namawadi aphelele e-ICU njengoba isifundazwe besingazifuni izinhlaka zesikhashana? Yiziphi izindawo ezibucayi ezibe nomthelela emazingeni aphezulu okufa kwabantu esifundazweni? Yiziphi izindlela zokungenelela ezizokwethulwa ukuze kuhoxiswe lowo mkhuba? Bekuxhunyanwa kanjani nemiphakathi mayelana nendlela yokubhekana ne-Covid-19 ekhaya kanye nesikhathi sokufuna usizo lwezokwelapha? Ingabe umgomo wawungowokuzithandela noma wawuyisibopho futhi ingabe lokho kwakuzokwaziswa ngokucacile kulabo ababezothola umgomo?

Isifinyezo sinikezwe ngu Iqembu Lokuqapha Amalungu ePhalamende

I-India igunyaze okubili (2) yenziwe e-india imigomo - Oxford-AstraZeneca's 'I-Covishield' kanye ne-Bharat Biotech'sI-Covaxin' ngokugunyazwa ukusetshenziswa okuphuthumayo. Nakhu esikwaziyo mayelana nokusebenza kahle kwale mithi yokugoma kuze kube manje:

• I-Covishield

Lo mgomo usungulwe ngabakwa- Inyuvesi yase-Oxford kanye nenkampani yezemithi yaseBrithani-eSweden i-AstraZeneca. Adar Poonawalla, Isikhulu Esiphezulu, ISerum Institute of India (SII) - okungumlingani wokukhiqiza we-AstraZeneca we-British-Swedish pharma giant – wathi umgomo uzoba Amaphesenti angama-90 kuye kwangama-95 asebenza kahle uma amashothi amabili ehlukaniswa cishe izinyanga ezi-2-3. “Uzobe uzwa izindaba ezinhle ezivela e-UK maduze nje… Kungaba umuthi wokugoma osebenza ngo-90-95% uma nje ugcina igebe lezinyanga ezimbili kuya kwezintathu phakathi komthamo 1 nomthamo 2. Bazokwenza lokho kube esidlangalaleni. nemibhalo.” I-Covishield, i-Poonawalla ingeziwe, umuthi wokugomela osebenza ngempumelelo ngokumelene ne-coronavirus yenoveli. Umuthi wokugoma uthathwa njengowomunye wemithi yokugoma ethembisa kakhulu e-India lapho izindleko nokusebenza kudlala indima enkulu. Ngokusobala, ngokungafani nemithi yokugoma iPfizer neModerna, ezisebenzisa indlela entsha ebizwa nge-mRNA, ezenza zibe yinkimbinkimbi, zibe ntekenteke futhi ngaleyo ndlela zidinga i-ultracold amazinga okushisa, I-Covishield umuthi wokugomela i-vector ohamba kancane kodwa oshibhile futhi okubalulekile, ungagcinwa uzinzile izinyanga eziyisithupha emazingeni okushisa ajwayelekile esiqandisi.

• I-Covaxin

I-Covaxin ithuthukiswe yinkampani yaseNdiya ye-biotechnology i-Bharat Biotech kanye nenhlangano yocwaningo lwezomtholampilo i-Indian Medical Research (ICMR). Umbiko we-NDTV ubiza i-Covaxin ngomuthi wokugoma ongasebenzi - enye yezindlela ezindala kakhulu zokugoma abantu - okusho ukuthi amagciwane aphelele, angasebenzi ajovwa emzimbeni ukuze avuse impendulo yokuzivikela komzimba. Lawa maqoqo e-coronavirus kumele akhuliswe, "abulawe" kusetshenziswa ikhemikhali noma ukushisa bese enziwa umuthi wokugoma, okwenza kube yinqubo ende, kusho umbiko.  I-Covaxin amafomu emvume athi abahlomulayo bazonikezwa ukunakekelwa ezibhedlela eziqokwe uhulumeni nezigunyaziwe uma kwenzeka kuba nemiphumela emibi kakhulu ngenxa yomgomo, kusho umbiko we-Times of India. Abahlomuli abathola i-Covaxin bazokhokhelwa isinxephezelo uma behlupheka izenzakalo ngenxa yomuthi wokugoma. Isinxephezelo sasiphakathi kwamaphuzu agqanyiswe phezu kwefomu lemvume elabelwe isikhungo sokugoma ngoLwesihlanu. Ngokwemibiko, “ukusebenza kahle komtholampilo kwe-Covaxin kusazosungulwa futhi kufundwa esigabeni sesi-3 sokuhlolwa komtholampilo”.

UHLELO lwe-SAHPRA ESOKUSETSHENZISWA KWE-IVERMECTIN KU-PROPHYLAXIS NOMA EKWELASHWENI KWE-COVID-19

Iyini i-ivermectin?

I-Ivermectin iyisidakamizwa esisetshenziswa kakhulu ekwelapheni nasekulawuleni izimuncagazi ezilwaneni futhi isetshenziselwa ukwelapha izifo eziningana zasezindaweni ezishisayo kubantu ezingavamile ukubonakala eNingizimu Afrika, kanye notwayi nezintwala zekhanda. Ivermectin kuyinto esuselwe zokwenziwa ekilasini antiparasitic of compounds eyaziwa ngokuthi avermectins.

ENingizimu Afrika ivermectin ibhaliselwe ukusetshenziswa ngaphansi koMthetho 36 ka-1947 (uMnyango Wezolimo) ukuze isetshenziswe ezilwaneni. Lokhu kusho ukuthi odokotela bezilwane kanye nabanye abasebenzi abaqeqeshiwe bavunyelwe ukuyinikeza njenge-ejenti elwa namagciwane ezinhlobonhlobo zezilwane. Umuthi okwamanje awubhalisiwe ukuthi usetshenziswe abantu, kodwa i-SAHPRA ngezikhathi ezithile inikeza izimvume zeSigaba 21 zokusebenzisa i-ivermectin ye-topical njengomkhiqizo ongabhalisiwe wokwelapha isiguli ngasinye esinezimo ezifana notwayi noma izintwala zekhanda.

Abaphenyi abaningana babike ukuthi lapho ihlolwa elabhorethri, i-ivermectin ivimbela ukuphindaphinda kwe-acute acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Uma kubhekwa ubhubhane lwamanje lwe-coronavirus-19 (COVID-19), lokhu ngokuqondakalayo kuthole ukunakwa okuningi kwabezindaba. Ngakho-ke, kuye kwenziwa izifundo ezimbalwa zomtholampilo ukuze kuhlolwe ukusebenza kahle kwe-ivermectin ekwelapheni ukutheleleka kwe-COVID-19.

Kwamanye amazwe lapho i-ivermectin ibhaliselwe ukusetshenziswa abantu, ukwakheka kokusetshenziswa komuntu kusetshenziswa ngaphandle kwelebula ekulawuleni izifo ze-Covid-19 lapho umthwalo wemfanelo womtholampilo wokuqapha ukuphepha nokusebenza ngempumelelo ulele kuye kuphela. Ngaphezu kwalokho, kunemibiko esabalele yokusetshenziswa kwe-ivermectin ukuvimbela noma ukwelashwa kwe-COVID-19 eNingizimu Afrika kusetshenziswa umkhiqizo wezilwane.

Umbono we-SAHPRA mayelana nokusetshenziswa kwe-ivermectin udluliselwe ngoDisemba 2020

Ngomhla zingama-22 kuZibandlela wezi-2020, i-SAHPRA yabonisa ukuthi maqondana nokusetshenziswa kwe-ivermectin ku-COVID-19, ukuthi “I-Ivermectin ayibonisiwe futhi ayigunyazwanga yi-SAHPRA ukuthi isetshenziswe kubantu. Ayikho idatha eqinisekisayo nge-ivermectin etholakalayo okwamanje ukuze isetshenziswe ekulawuleni izifo ze-COVID-19. Ngokuphathelene nokuphepha nokusebenza kahle abukho ubufakazi bokusekela ukusetshenziswa kwe-ivermectin futhi asinabo ubufakazi bokuhlolwa komtholampilo ukuze siqinisekise ukusetshenziswa kwayo.

Uhlu Lwemithi Ebalulekile (EML) I-COVID-19 Ukubuyekezwa Okusheshayo kwe-ivermectin (21 December 2020)

I-SAHPRA iphinde iphawule ukuthi Ikomidi elincane le-EML COVID-19 lishicilele Ukubuyekezwa Okusheshayo ku-ivermectin (21 December2020) lapho baphetha ngokuthi:

• Ikhwalithi isiyonke yokuhlolwa okungahleliwe okubandakanya i-ivermectin ezigulini ze-COVID-19 iphansi kakhulu.
• Kusukela ebufakazini obutholakalayo bokulawula okungahleliwe, i-ivermectin ayiphakeme kune-placebo ngokwemibandela yokunciphisa umthamo wegciwane egazini noma ukuqhubeka komtholampilo. Abukho ubufakazi obuvela ezinhlolweni zokulawula ezingahleliwe zanoma yikuphi ukuncipha kokufa.

Iziguli ezifanele ezine-COVID-19 eNingizimu Afrika kufanele zicatshangelwe ukuze zibhaliswe ezivivinyweni zokwelashwa ezifanele.

Ukubuyekezwa kwe-SAHPRA kwedatha yamanje yokusetshenziswa kwe-ivermectin ekwelapheni noma ekuvimbeleni izifo ze-COVID-19

Ukusabela kule ntshisekelo ekhulayo ye-ivermectin kanye nenani elikhulayo ledatha ngokusetshenziswa kwayo ekwelashweni nasekuvimbeleni i-COVID-19, i-SAHPRA manje isibuyekeze futhi, idatha etholakalayo evela ezifundweni zomtholampilo.

Ukuhlaziywa kwakamuva kwe-meta, okungukuthi ukubuyekezwa okuhlelekile, kwedatha yesilingo sokwelashwa kwe-COVID-19 senziwe nguDkt Andrew Hill wase-University of Liverpool, exhaswe yi-Unitaid okuwuhlelo lwezempilo lomhlaba wonke olusebenzisana nabalingani ukuletha mayelana namasu amasha okuvimbela, ukuhlonza kanye nokwelapha izifo ezinkulu emazweni anemali engenayo ephansi naphakathi). Nakuba lo mbiko utholakala kabanzi emphakathini, awukakashicilelwa kujenali yesayensi ebuyekezwe ngontanga.

Ukuhlaziywa kwe-meta kuphethe ngokuthi ukusetshenziswa kwe-ivermectin ekulawuleni izifo ze-COVID-19 kuhlotshaniswa nesikhathi esisheshayo sokukhishwa kwegciwane, isikhathi esifushane sokulaliswa esibhedlela namazinga aphezulu okululama emtholampilo kanye nokuthuthukiswa okuthile kumazinga okusinda.

Kodwa-ke, ukuhlaziywa kwe-meta kuphinde kwaphetha ngokuthi kudingeka idatha eyengeziwe yesilingo somtholampilo esingahleliwe ukuze kuqinisekiswe inzuzo yomtholampilo ezifweni ze-COVID-19 kanye nokuchaza uhlobo lomthamo olulungiselelwe. Ngaphezu kwalokho, uDkt Hill uhlonze inani lemikhawulo ngedatha evela kulokhu kuhlolwa komtholampilo, okuhlanganisa nalokhu:

• Imiphumela yamanje isuselwe ekuhlolweni okungahleliwe okulinganiselwe
• Kungase kube nokuchema kokushicilela
• Ukuhlolwa ngakunye okubuyekeziwe bekunamandla ezibalo alinganiselwe
• Izivivinyo ezimbalwa bezinelebula elivulekile elethula ithuba lokuchema komphenyi
• Ibanga lemithamo nobude besikhathi akuzange kufane
• Amaphoyinti okugcina ahluka phakathi kwezilingo

Ekuphetheni kwakhe, uDkt Hill uveze ukuthi izivivinyo zomtholampilo eziklanywe kahle ziyadingeka ukuze kuhlinzekwe ngemininingwane eyanele yesayensi ukuze kusetshenziswe i-ivermectin ekwelapheni i-COVID-19.

Ngokusekelwe ku-Hill meta-analysis kanye ne-Front Line COVID-19 Critical Care Alliance (FLCCC), i-SAHPRA iphawula lokhu okulandelayo:

• Ikhwalithi isiyonke yokuhlolwa komtholampilo okungahleliwe okubandakanya i-ivermectin ezigulini ze-COVID-19 impofu futhi ayinawo amandla. Kusukela ebufakazini obutholakalayo bokuhlolwa kokulawulwa okungahleliwe, i-ivermectin ibonakala ingekho ngaphezu kwe-placebo ngokwemibandela yokunciphisa umthamo wegciwane egazini noma ukuqhubeka komtholampilo. Abukho ubufakazi obuvela ezinhlolweni ezilawulwa ngokungahleliwe zanoma yikuphi ukuncipha kokufa.
• Ucwaningo luyehluka ngokuphathelene namaqembu abantu abafakwe ocwaningweni okungukuthi iziguli ezilaliswa ngaphandle, ukulaliswa esibhedlela kusenesikhathi, iziguli ezilaliswa isikhathi eside esibhedlela, iziguli ezise-ICU njll.
• Imithamo ezifundweni ezehlukene ayifani. Ngenxa yalokho, ukutholwa komthamo akukwazi ukusungulwa ukuze kuphathwe ngendlela ephephile futhi ephumelelayo izifo ze-COVID-19 (noma ngabe okokwelashwa noma ukuvimbela).
• I-Ivermectin ihlolwe ngeminye imithi eminingana ehambisanayo (efakazelwe futhi ayinabufakazi, iyodwa noma ihlanganiswe neminye imithi) futhi lokhu kukhawulela iziphetho ezingenziwa mayelana nokuphepha nokusebenza kwe-ivermectin.
• Lezi zifundo zinemikhawulo eyengeziwe ekhonjwe ababuyekezi ngokwabo njengoba kukhonjisiwe ngenhla, okuphawuleka kakhulu ukuthi ayikho idatha yesilingo eyanele etholakalayo njengamanje. Kodwa kuyaphawulwa ukuthi kuzoba neminye imininingwane yomtholampilo etholakala maphakathi kuya ekupheleni kukaJanuwari 2021. I-SAHPRA ikulindele ngabomvu lolu lwazi ukuze ibuyekeze isimo sayo ngokusetshenziswa kwe-ivermectin ekulawuleni izifo ze-Covid-19.

I-SAHPRA iphawula ukuthi kuze kube manje, azikho izincomo ezinhle zokusetshenziswa kwe-ivermectin ekulawuleni ukutheleleka nge-Covid-19 yinoma yisiphi isiphathimandla esilawulayo i-SAHPRA enezivumelwano zokuthembela kuso, isb. USFDA, EMA, MHRA, njll., kanye nokuthi i-WHO ayincomi okwamanje ukusetshenziswa kwe-ivermectin ekwelapheni noma ekuvimbeleni izifo ze-COVID-19.

Ngaphezu kwalokho, umbiko omayelana ne-pharmacokinetics ye-ivermectin uphethe ngokuthi 'Okutholakele kokuqala kusikisela ukuthi imithamo evamile ye-ivermectin ngeke iphumele ekugxilweni okusebenzayo, nokuthi imithamo engavamile yokufinyelela ukugxila okusebenzayo ingase ibangele ubuthi obungamukeleki ezigulini ze-COVID-19.' (Ref: Pharmacometrics Africa kanye ne-CERTARA).

Kubalulekile futhi ukuqaphela ukuthi nakuba i-ivermectin ibhekwa njengephephile ngokuvamile, imiphumela emibi ihlanganisa ukuqubuka kwesikhumba, isicanucanu, ukuhlanza, isifo sohudo, ubuhlungu besisu, ukuvuvukala kobuso noma esithweni, izehlakalo ezimbi ze-neurologic (isiyezi, isiyezi, nokudideka), ukwehla ngokuzumayo. umfutho wegazi, ukuqubuka okukhulu kwesikhumba okungase kudinge ukulaliswa esibhedlela nokulimala kwesibindi (isibindi). Ukungajwayelekile kokuhlolwa kwaselabhorethri kufaka ukwehla kwenani lamaseli amhlophe kanye nokuhlolwa kwesibindi okuphakeme.

Isimo samanje sezicelo ku-SAHPRA ukuze kugunyazwe ukuhlolwa komtholampilo noma ukubhaliswa

Njengamanje, azikho izicelo zokuhlolwa komtholampilo ze-ivermectin ezithunyelwe kwa-SAHPRA ukuze zibuyekezwe. I-SAHPRA ikhuthaza ukuthunyelwa kwezicelo zokuhlolwa komtholampilo eziklanyelwe ukusungula ukuphepha nokusebenza kwe-ivermectin ekulawuleni izifo ze-Covid-19 kukho kokubili ukwelashwa kanye nokuvimbela futhi izibophezele ekusheshiseni ukubuyekezwa kwazo. Le ndlela ike yasetshenziswa ngaphambilini ezicelweni zesilingo somtholampilo zeminye imithi yophenyo ebihlolelwa ukuphathwa kwe-COVID-19.

Ngaphezu kwalokho, i-SAHPRA ayikatholi zicelo zokubhalisa i-ivermectin ukuze ivikeleke noma ukwelashwa kwe-COVID-19 kodwa izimisele ukusheshisa ukubuyekezwa kwanoma yisiphi isicelo esinjalo uma sithunyelwa.

Isiphetho

Okwamanje azikho izicelo zokuhlolwa komtholampilo noma zokubhaliswa kwe-ivermectin yokwelashwa noma njenge-prophylaxis ye-COVID-19. Kodwa-ke, i-SAHPRA ikhuthaza futhi yeseka zonke izifundo zesayensi eziklanywe kahle, ezigunyazwe ngokokuziphatha, eziklanyelwe ukuhlonza imithi emisha noma ekhona kakade esetshenziselwa ukwelapha noma ukuvimbela i-COVID-19. I-SAHPRA iphinda igcizelela ukuzibophezela kwayo ekusheshiseni ukubuyekezwa kwalolo cwaningo. Ngaphezu kwalokho, njengesiphathimandla esilawulayo saseNingizimu Afrika, i-SAHPRA izoqhubeka nokuhlola noma yiziphi izincwadi ezibuyekezwe ontanga abasafufusa noma idatha ngokusetshenziswa kwe-ivermectin ekwelapheni i-COVID-19, futhi iphawula ukuthi ngokwerejista yezivivinyo zomtholampilo zomhlaba wonke, idatha eyengeziwe kufanele itholakale. phakathi nezinyanga ezimbalwa ezizayo. I-SAHPRA izophinde icabangele ukunika amandla ukufinyelela ekwakhiweni okugunyaziwe kwe-ivermectin okuhloselwe ukusetshenziswa abantu, okuhlanganisa nokugunyazwa kweSigaba 21, inqobo nje uma isicelo esinjalo sisekelwa ubufakazi benkomba eceliwe futhi silungisiwe ngokusekelwe ekuhloleni inzuzo engozini ehlanganisa idatha yokuphepha kanye nokusebenza komtholampilo. .